SZABMU AHS 2026 Blood Free Quiz 7

1. What characterizes disseminated intravascular coagulation?

A. Excessive coagulation and bleeding B. Only bleeding C. Only thrombosis D. Bone marrow failure

2. What is the primary defect in hereditary spherocytosis?

A. Hemoglobin disorder B. Membrane protein defect C. Enzyme deficiency D. Iron overload

3. How is G6PD deficiency inherited?

A. Autosomal recessive B. X-linked C. Autosomal dominant D. Mitochondrial

4. What is the molecular defect in PNH?

A. T-cell disorder B. Somatic mutation in PIGA C. B-cell lymphoma D. Platelet defect

5. Which transcription factor mediates the hypoxic induction of erythropoietin?

A. HIF-1α B. NF-κB C. AP-1 D. STAT3

6. Which peptide hormone regulates systemic iron levels by controlling ferroportin?

A. Heme oxygenase B. Hepcidin C. Transferrin D. Ferritin

7. What causes anemia of chronic disease?

A. EPO deficiency B. Iron deficiency C. Hepcidin-mediated iron sequestration D. Bone marrow failure

8. Which test measures long-term glycemic control?

A. Acute glucose level B. HbA1c C. Fructosamine D. Albumin

9. What is the Bohr effect?

A. Increased oxygen unloading at lower pH B. Decreased oxygen unloading at lower pH C. No effect D. Increased affinity for oxygen

10. What effect does 2,3-BPG have on hemoglobin oxygen affinity?

A. Increases affinity B. Decreases affinity C. No effect D. Binds to heme iron