SZABMU AHS 2026 Blood Free Quiz 9

1. Which hormone regulates thrombopoiesis?

A. Thrombopoietin B. Erythropoietin C. Interleukin-6 D. Granulocyte colony-stimulating factor

2. What is the mechanism of ITP?

A. Autoantibodies against RBCs B. Autoantibodies against platelets C. Autoantibodies against clotting factors D. Antibodies against bone marrow

3. What is the primary defect in von Willebrand disease?

A. Factor VIII deficiency B. vWF deficiency C. Platelet count low D. Fibrinogen defect

4. Which clotting factors are deficient in hemophilia A and B?

A. Factor VIII deficiency (A), factor IX (B) B. Factor IX (A), factor VIII (B) C. Factor VII (A), factor X (B) D. Factor XI (A), factor XII (B)

5. Which coagulation pathway is assessed by PTT?

A. Intrinsic pathway (PTT) B. Extrinsic pathway (PT) C. Common pathway D. Fibrinolytic activity

6. What does prothrombin time (PT) assess?

A. Intrinsic pathway B. Extrinsic pathway (PT) C. Common pathway D. Platelet function

7. What is the standardized PT used for monitoring warfarin?

A. PT ratio without standardization B. INR C. APTT ratio D. D-dimer

8. Which genetic defect causes resistance to activated protein C?

A. Antithrombin deficiency B. Protein C deficiency C. Factor V Leiden (APC resistance) D. Prothrombin G20210A

9. Which deficiency leads to reduced inhibition of thrombin and factor Xa?

A. Antithrombin III deficiency B. Protein C deficiency C. Protein S deficiency D. Dysfibrinogenemia

10. What is the clinical significance of lupus anticoagulant?

A. Decreases thrombosis risk B. Increases thrombosis risk C. Causes bleeding D. No effect